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Y2H References

REVIEWS

Allen JB, Walberg MW, Edwards MC and Elledge SJ. 1995. Finding prospective parterns in the library: the two-hybrid system and phage display find a match. TIBS 20:511-516

Auerbach D, Thaminy S, Hottiger MO, Stagljar I. 2002. The post-genomic era of interactive proteomics: facts and perspectives. Proteomics.2:611-623.

Brent R and Finley RL 1997. Understanding gene and allele function with yeast-two hybrid methods. Annu. Rev. Genet. 31: 663-704

Uetz PH, Hughes RE and Fields S. 1998. The two-hybrid system: finding likely partners for lonely proteins. Focus 20:62-64

RESEARCH CLASSICS

Fields S and Song, O. 1989. A novel genetic system to detect protein-protein interactions. Nature 340:245-6.

Chien CT, Bartel PL, Sternglanz R, Fields S. 1991. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc Natl Acad Sci U S A. 88:9578-82

STRAIN AND VECTORS

James P, Halladay J and Craig, EA. 1996. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144:1425-1436.

OTHER SITES OF INTEREST

NCI/Nature Pathway Interaction Database

Erica Golemis' list of common false positives

String: functional protein association networks

Pathcalling yeast interaction database

Information Hyperlinked over Proteins

Biomolecular Interaction Network Database

Drosophila Protein Interaction Map database

Jena Centre for Bioinformatics (JCB)_web tools

MIF
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Contact: Eileen Maher