Symposium Series in Developmental and Molecular Toxicology

Horizons in Developmental Toxicology and Developmental Biology

June 3 - 5, 1999

Sponsor:

EHS Center for Developmental and Molecular Toxicology University of Wisconsin-Madison Madison, Wisconsin

NIEHS

GOALS FOR THE MEETING

UW-Madison EHS Center for Developmental and Molecular Toxicology is sponsoring a series of annual symposiums highlighting new ideas and approaches to Developmental Toxicology. Each symposium will focus on the research perspectives from one of the Center's Research Cores. This first symposium centers on how new concepts from Developmental Biology can shape current and future thinking about mechanisms of developmental disruption in humans, and will include roundtable discussions following each of the three sessions to formulate future research goals. Additionally, this symposium will establish communication with biological research scientists with no previous specialized knowledge in the field of developmental biology. A public forum on Environmental Health issues will also be included.

CONFERENCE SCHEDULE

Thursday, June 3, 1999

6:30 PM Registration, Gallery, State Historical Society

7:00 PM Opening Remarks Richard E. Peterson, Ph.D., Deputy Director, EHS Center

KEYNOTE ADDRESS

7:15 PM Topobiology: Place-Dependent Gene Regulation and Morphogenesis

Gerald Edelman, Ph.D., Nobel Laureate in Medicine

Scripps Research Institute

Friday, June 4, 1999

8:00 AM Registration, Gallery, State Historical Society

8:30 AM Introduction

Colin R. Jefcoate, Ph.D., Director, EHS Center

Session Facilitators: Susan Smith, Ph.D., and John Fallon, Ph.D.

PLENARY LECTURE

8:45 AM Birth Defects Research: A Path to Prevention

Kathleen Sulik, Ph.D.

University of North Carolina at Chapel Hill

Chemically Induced Birth Defects in Humans

9:30 AM Fetal Alcohol Syndrome in Humans

Kenneth Lyons Jones, M.D.

University of California San Diego Medical Center

10:00 AM Break

10:30 AM Identifying and Understanding Causes of Human Birth Defects

Lewis Holmes, M.D.

Harvard Medical School, Boston

11:00 AM Gene-Environment Interactions in Human Craniofacial Anomalies

Jeffrey Murray, M.D.

University of Iowa

11:30 PM Roundtable Discussion

12:00 PM Lunch

Animal Models for the Study of Developmental Toxicology I

Session Facilitators: Amy Moser, Ph.D., and Anne Griep, Ph.D.

1:30 PM Flies on Drugs: Genetic Approaches to Acute and Chronic Responses

to Alcohol and Psychostimulants

Ulrike Heberlein, Ph.D.

University of California-San Francisco

2:00 PM A Putative Catenin-Cadherin System Mediates Morphogenesis of the

Caenorhabditis elegans Embryo

Jeffrey Hardin, Ph.D.

University of Wisconsin-Madison

2:30 PM Genetic Dissection of Neural Function in Drosophila Using

Temperature-Sensitive Paralytic Mutants

Barry Ganetzky, Ph.D.

University of Wisconsin-Madison

3:00 PM Break

3:30 PM Insertional Mutagenesis in Zebrafish: Identification of Novel Genes

Essential for Embryonic Development

Nancy Hopkins, Ph.D.

Massachusetts Institute of Technology

4:00 PM Roundtable Discussion

5:00 PM Poster Discussion Session (location to be announced), refreshments

Saturday, June 5, 1999

Animal Models for the Study of Developmental Toxicology II

Session Facilitators: Theodore Golos, Ph.D., and Nellie Laughlin, Ph.D.

9:00 AM The Developing Limb as a Model System to Study Embryonic

Pattern Formation

John Fallon, Ph.D.

University of Wisconsin-Madison

9:30 AM Animal Model for Autism in Humans

Patricia Rodier, Ph.D.

University of Rochester

10:00 AM Rodent Model of Hypovitaminosis A for the Study of

Hindbrain Development

Margaret Clagett-Dame, Ph.D.

University of Wisconsin-Madison

10:30 AM Break

11:00 AM A Primate Model of Moderate Level Fetal Alcohol Exposure

Mary Schneider, Ph.D.

University of Wisconsin-Madison

11:30 AM Roundtable Discussion

12:00 PM Lunch

PUBLIC FORUM

Facilitators: Colin Jefcoate, Ph.D., and Ralph Albrecht, Ph.D.

1:30 PM Probing Public Issues in Environmental Health

Kevin Niemi, Ph.D. and Thomas Zinnen, Ph.D.

University of Wisconsin-Madison

GENERAL INFORMATION

Dates: June 3-5, 1999

Location: The State Historical Society of Wisconsin

816 State Street

Madison, WI 53706

Deadline: May 21, 1999

Conference Fees (Late fee after May 21):

Fee includes registration and associated materials, the right to submit poster, and three refreshment breaks.

__ Faculty/Staff: $100 Late fee: $150

__ UW Faculty/Staff: $35 Late fee: $50

__ Students/Postdocs: $25 Late fee: $25

Cancellation Policy: A full refund will be given if you cancel your reservation before May 21, 1999. After May 21, a $15 cancellation fee will be charged.

Lodging: A block of rooms has been reserved at the Howard Johnson Plaza Hotel, 525 West Johnson Street, Madison, WI 53703. Telephone: 608-251-5511, FAX: 608-251-4824.

You must state that you are attending the Horizons in Developmental Toxicology and Developmental Biology Symposium to receive the special rate.

This block of rooms will be held until May 3, after which space will be available on a first-come basis.

Posters: Attendees, particularly students and postdoctoral trainees, are encouraged to submit abstracts for the presentation of posters of their work. Abstracts should be submitted as a single-page, nonjustified text, using 12 point Times Roman font, with a margin of no less than 1/2 inch on each side. Space is limited. Applicants will be notified if their Abstract is accepted. Send Abstracts to the EHS Center by May 3, 1999. You must be registered for the conference to present a poster. A limited number of awards (registration fee plus up to $500 for expenses) will be available to qualified students and postdoctoral trainees. For more information, contact the EHS Center at EHSCenter@macc.wisc.edu, or at the address or telephone number listed below.

For Additional Information: Contact EHS Center for Developmental and Molecular Toxicology, University of Wisconsin-Madison, 550 Babcock Drive, B157 Steenbock Library, Madison, WI 53706, Telephone: 608-263-5556, FAX: 608-262-5245; e-mail: EHSCenter@macc.wisc.edu.

Mail or FAX to:

CALS Outreach Services 620 Babcock Drive Madison, WI 53706 Phone: 608-263-1672 FAX: 608-262-5088

REGISTRATION FORM:

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