The Translational Genomics Facility (TGF) is a core facility committed to serving the genome-editing needs at the University of Wisconsin and worldwide by providing expert services in consultation, design, reagent preparation and purification.

TGF was established to serve a strong, grass-roots need on campus. In February 2014, UW-Madison held a campus-wide workshop with the goal of bringing together those interested in CRISPR/Cas9. As interested scientists poured through the entrances and packed the aisles of the Genetics/Biotechnology Center Auditorium, it was clear there was a vigorous demand for genome editing resources on campus. The group organizing the workshop came to be called GEEWisc.

Subsequent GEEWisc meetings sought to determine the types of campus resources that could best address genome editing needs across campus. A resoundingly strong request was for a core facility offering CRISPR expertise and delivering genome-editing services. To meet this need, TGF was established at the UW-Madison Biotechnology Center in March 2015, directed by Dr. C. Dustin Rubinstein.

Today, TGF serves a diverse array of clients across campus and beyond. While the most vigorous demand is for the generation of genome-edited mice and rats in partnership with the Transgenic Animal Facility, the TGF is also developing swine models, cell line models, bovine models, and zebrafish models. 
Captain Genome
Dustin Rubinstein
Facility Director
Email: crubinstein@wisc.edu

Background:
Dr. Rubinstein received his PhD from Cornell University in 2008. He has extensive experience in genetics applied towards a diverse array of research topics, including neuroscience, behavior, reproduction, and bioinformatics. He has always sought to generate tools to best address important research questions. Dr. Rubinstein was most recently a member of a team led by Profs. Melissa Harrison, Kate O'Connor-Giles, and Jill Wildonger, and this group was the first to publish the use of CRISPR/Cas9 in Drosophila. In this team, he helped generate a dozen genome-edited flies and built a website to assistant CRISPR/Cas9 project design.



Brent
Brent Lehman
Research Specialist
Email: bplehman@wisc.edu

Background:
Brent received his B.S. in Biochemistry and Molecular Biology from the University of Wisconsin-Eau Claire in 2012. He then continued on to complete his M.S. in Biochemistry at Iowa State University in 2015. Brent trained in the lab of Tom Bobik where he learned genetic recombineering methods. 


Lexie
Lexie Roeder
Undergraduate Research Assistant
Email: arroeder@wisc.edu

Background:
Lexie is currently in her Junior year at the University of Wisconsin-Madison. She is pursuing her B.S. in both Pharmacology-Toxicology and Biology, while earning certificates in leadership in education. Lexie began working at TAF in August of 2015. She anticipates graduating in May of 2018 and hopes to continue on to medical school to pursue her passion within pediatrics.


Kris Carlson
Undergraduate Research Assistant
Email: kcarlson9@wisc.edu

Background:
Kris is currently in her Sophomore year at the University of Wisconsin-Madison. She is pursuing her B.S. in Biology. Kris began working at TAF in August of 2015. She anticipates graduating in May of 2018 and hopes to continue on within the field of research.