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University of Wisconsin–Madison

Bioinformatics Resource Center

The Bioinformatics Resource Center (BRC) is a facility within the UW Biotechnology Center (UWBC) that is dedicated to assisting researchers with their data analysis needs. We have knowledge and experience with a variety of common sequencing related projects, DNA-seq, ChIP-Seq, RNA-Seq, 16S metagenomics, and small RNA analyses. We are supported by a number of different labs and departments that require advanced support and new workflow development. Additionally, we offer consultation and computation using established pipelines. See our policies page for more information.

Acknowledgement and authorship guideline

We kindly ask you to acknowledge any BRC contribution in your presentation and publication. Please consider granting authorship if you feel we have made an intellectual contribution to the work. We rely on public acknowledgments of our work when applying for funding.

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Data Analysis

Free Design Consultation

We offer free consultations as part of the initial experimental design. We want to ensure that you have thought about all the necessary design components before you conduct your experiment. This way BRC has high quality data when it comes time for us to analyze the data. We offer this service at no charge because it is more cost effective to catch design errors before we start the analysis. 

Data Analysis and General Consultation ($/hr)

We will offer custom analysis or training at our hourly rate.

Grant Support (% effort)

We can provide project specific analysis beyond our standard pipeline services when we are written into grants. This may be a cheaper option for labs requiring a lot of analysis time as we dedicate a percent of our effort to the project.


Workshops


Server Access

The BRC manages access to UWBC Linux servers. These servers are for the purposes of data analysis only. A BRC account is needed to access server resources. Access permissions and data storage are tied to a BRC account and not a server. This separates our compute costs from the data storage and account maintenance overhead. All servers benefit from our high availability storage system and access to the BRC common software directory.

Computer lab

The BRC computer lab is located in room 1260 of the Biotechnology Center. The computer lab contains three workstations which may be used to access the AGAR servers. Key card access is granted upon request to users with an active BRC account. We request that users reserve a server for the entire duration the server will be processing the data.

Remote access

Users can rent BRC servers at cost. Rented BRC servers are dedicated to a specific account and allow for remote access from any campus location or from off campus via VPN.

Software & Genome Data

The BRC staff uses many common bioinformatic software packages, and maintains alignment indexes for popular reference genomes. All BRC users have access to our software directory (/mnt/software) and genomes directory (/mnt/genomes). Software programs and genome indexes are maintained as needed. Users may request updates and/or install additional software according to our policy.